The 10^th International Congress on SDS will take place in Cambridge from 18-21 April 2023. It will present outstanding new research and clinical developments from around the world relevant to those with an interest in SDS and related ribosomopathies. The theme of this year’s Congress is ‘From ribosome assembly to therapy’. Day 2 of the Congress focuses on ribosome assembly and features a world leading collection of speakers including Laura Attardi, Nenad Ban, Maria Barna, Sebastian Klinge, Vikram Panse and Alan Warren. Other research areas covered include translational control, genetics, gene therapy and imaging.